Seizures can result in a pathological suspension of awareness. We are currently working on extending connectivity analysis towards a dynamical understanding of regions involved with these changes, as well as applying multivariate pattern analysis to predict different types of epileptic syndromes from fMRI activity.

Dynamical analysis of inter-ictal activity in temporal lobe epilepsy.

Dynamical analysis of inter-ictal activity in temporal lobe epilepsy.

Journal reference:

Laufs H, Rodionov R, Thornton R, Duncan JS, Lemieux L, Tagliazucchi E. Altered fMRI connectivity dynamics in temporal lobe epilepsy might explain seizure semiology (2014). Frontiers in Neurology.